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Tag: medicinal chemistry

  • 1
    Mar
    Medicinal Chemistry

    kanhaiyalalbardwa32@gmail.com

    Biosynthesis of catecholamine and Their Catabolism

    Introduction Catecholamines are the neurotransmitters containing catechol ring with two hydroxyl side groups in their structure. The biosynthesis of catecholamines constitutes a fascinating and intricate processes in human body. Catecholamines including dopamine, norepinephrine, epinephrine are essential neurotransmitter involved in mood regulation, stress response and cardiovascular function. Understanding the biosynthesis of catecholamines is crucial for unravelling…

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  • 29
    Feb
    Medicinal Chemistry

    kanhaiyalalbardwa32@gmail.com

    Factors Affecting Drug Metabolism

    Factors affecting drug metabolism Drug metabolism is the metabolic breakdown of drugs, through specialised enzymatic systems. Liver is the principal site of drug metabolism, additional sites are kidney, gut, lungs and plasma. Once the drug shows its pharmacological action, the remaining amount of drug should be excreted from body. Metabolism plays an important role in…

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  • 28
    Feb
    Medicinal Chemistry

    kanhaiyalalbardwa32@gmail.com

    Drug Metabolism Principles- Phase I and Phase II Reactions

    Introduction The drug is eliminated irreversibly from the body by two processes, one is metabolism and other is excretion. The process of biotransation of drugs or non-essential foreign chemicals in the body, to remove out of the body this process is referred as drug metabolism. Unabsorbed drug or non-essential chemical is made hydrophilic to remove…

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  • 29
    Jan
    Blog, Medicinal Chemistry

    kanhaiyalalbardwa32@gmail.com

    Medicinal Chemistry: Physicochemical Properties in Relation to Biological Action

    Medicinal chemistry is a branch of chemistry which deals with synthesis, design and development of pharmaceutical drug. Medicinal chemistry combines expertise from pharmacology and chemistry. Generally medicinal chemists work to make new compounds, determine their effects, modify the structure to minimize the side effects and study the pharmacokinetics properties of the drug. In this article…

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