Pharmacy Practice MCQ, in this article we will solve, Practice MCQ under subject Microbiology. Read following article for your reference.
-
What is the primary purpose of sterility testing in pharmaceutical products?
-
a) To determine the potency of the product
-
b) To confirm the absence of viable microorganisms
-
c) To check the pH levels
-
d) To assess the color of the product
-
-
Which of the following pharmacopeias provide guidelines for sterility testing?
-
a) IP (Indian Pharmacopoeia)
-
b) BP (British Pharmacopoeia)
-
c) USP (United States Pharmacopeia)
-
d) All of the above
-
-
What is a common method used for sterility testing of liquid products?
-
a) Filtration
-
b) Centrifugation
-
c) Sedimentation
-
d) Precipitation
-
-
Which medium is typically used for the sterility testing of anaerobic microorganisms?
-
a) Fluid Thioglycollate Medium
-
b) Soybean Casein Digest Medium
-
c) Sabouraud Dextrose Medium
-
d) MacConkey Agar
-
-
What is the recommended incubation temperature range for sterility testing according to USP?
-
a) 15-20°C
-
b) 20-25°C
-
c) 30-35°C
-
d) 35-37°C
-
-
How long are samples typically incubated during sterility testing?
-
a) 7 days
-
b) 10 days
-
c) 14 days
-
d) 21 days
-
-
Which method is commonly used for sterility testing of solid products?
-
a) Membrane filtration
-
b) Direct inoculation
-
c) Centrifugation
-
d) Ultrasonication
-
-
In sterility testing, what is the purpose of using a negative control?
-
a) To confirm the growth of microorganisms
-
b) To ensure no contamination has occurred
-
c) To verify the effectiveness of the product
-
d) To measure the potency of the product
-
-
Which pharmacopeia specifies the use of Soybean Casein Digest Medium for sterility testing?
-
a) IP
-
b) BP
-
c) USP
-
d) All of the above
-
-
What is the importance of using positive controls in sterility testing?
-
a) To confirm the absence of contamination
-
b) To verify the sterility of the medium
-
c) To ensure the test system can support the growth of microorganisms
-
d) To measure the chemical properties of the product
-
-
Which method is suitable for sterility testing of ophthalmic products?
-
a) Direct inoculation
-
b) Membrane filtration
-
c) Centrifugation
-
d) Sedimentation
-
-
What is the role of Fluid Thioglycollate Medium in sterility testing?
-
a) It supports the growth of aerobic microorganisms
-
b) It supports the growth of anaerobic microorganisms
-
c) It inhibits the growth of fungi
-
d) It acts as a preservative
-
-
Which of the following is a key consideration when selecting a sterility testing method for a product?
-
a) The volume of the product
-
b) The type of microorganisms expected
-
c) The physical state of the product (solid, liquid, etc.)
-
d) All of the above
-
-
Which sterility testing method involves passing the test sample through a filter membrane?
-
a) Direct inoculation
-
b) Membrane filtration
-
c) Centrifugation
-
d) Ultrasonication
-
-
In the context of sterility testing, what does IP stand for?
-
a) International Pharmacopoeia
-
b) Indian Pharmacopoeia
-
c) Internal Procedure
-
d) Inoculation Protocol
-
-
Which type of product is most likely to be tested using the membrane filtration method?
-
a) Powders
-
b) Liquids
-
c) Tablets
-
d) Ointments
-
-
What is the significance of the 14-day incubation period in sterility testing?
-
a) To allow sufficient time for slow-growing microorganisms to proliferate
-
b) To shorten the testing process
-
c) To increase the accuracy of pH measurement
-
d) To ensure complete chemical reaction
-
-
Which medium is typically used for the detection of fungi in sterility testing?
-
a) Sabouraud Dextrose Medium
-
b) Fluid Thioglycollate Medium
-
c) Soybean Casein Digest Medium
-
d) Nutrient Agar
-
-
What is the main objective of sterility testing in pharmaceutical products?
-
a) To verify the chemical composition of the product
-
b) To ensure the product is free from viable contaminating microorganisms
-
c) To measure the product’s viscosity
-
d) To determine the product’s expiry date
-
-
In sterility testing, what is the role of aseptic technique?
-
a) To promote the growth of microorganisms
-
b) To prevent contamination of the test samples
-
c) To speed up the testing process
-
d) To alter the pH of the medium
-
-
Which of the following is a key factor in ensuring the accuracy of sterility tests?
-
a) Proper sample size
-
b) Sterility of testing equipment
-
c) Appropriate incubation conditions
-
d) All of the above
-
-
What does BP stand for in the context of pharmacopeia?
-
a) Basic Pharmacology
-
b) British Pharmacopoeia
-
c) Biological Product
-
d) Bacteriological Protocol
-
-
What is the purpose of using incubators in sterility testing?
-
a) To accelerate the reaction between chemicals
-
b) To maintain optimal temperature conditions for microbial growth
-
c) To preserve the physical state of the product
-
d) To measure the concentration of microorganisms
-
-
What is one of the main challenges in sterility testing of solid products?
-
a) Ensuring complete dissolution of the product
-
b) Maintaining constant temperature
-
c) Measuring the product’s color
-
d) Avoiding contamination from the environment
-
-
Which regulatory guideline specifies the use of Fluid Thioglycollate Medium for sterility testing?
-
a) IP
-
b) BP
-
c) USP
-
d) All of the above
-
-
What is the significance of pering sterility testing on ophthalmic products?
-
a) To check the pH of the product
-
b) To ensure the product does not cause eye infections
-
c) To determine the viscosity of the product
-
d) To measure the concentration of active ingredients
-
-
Which method is NOT typically used for sterility testing of pharmaceutical products?
-
a) Direct inoculation
-
b) Membrane filtration
-
c) Centrifugation
-
d) HPLC
-
-
What is the role of positive controls in sterility testing?
-
a) To confirm the effectiveness of the disinfectant
-
b) To ensure the test system can support microbial growth
-
c) To verify the pH of the medium
-
d) To check the color of the product
-
-
Which of the following is a critical parameter to monitor during the incubation period in sterility testing?
-
a) pH of the medium
-
b) Temperature
-
c) Light intensity
-
d) Air pressure
-
-
What is the primary reason for pering sterility testing on pharmaceutical products?
-
a) To confirm the absence of viable contaminating microorganisms
-
b) To measure the chemical properties of the product
-
c) To assess the physical appearance of the product
-
d) To determine the product’s shelf life
-
For more regular updates you can visit our social media accounts,
Instagram: Follow us
Facebook: Follow us
WhatsApp: Join us
Telegram: Join us
