Pharmacy Practice MCQ, in this article we will solve, Practice MCQ under subject Microbiology. Read following article for your reference.
Evaluation Of Bactericidal & Bacteriostatic » PHARMACAREERS
1. What is the primary function of bactericidal agents?
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a) Inhibit bacterial growth
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b) Kill bacteria
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c) Promote bacterial growth
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d) Neutralize toxins
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What is the primary function of bacteriostatic agents?
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a) Inhibit bacterial growth
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b) Kill bacteria
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c) Promote bacterial growth
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d) Neutralize toxins
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Which test is commonly used to evaluate the bactericidal activity of a substance?
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a) Kirby-Bauer disk diffusion test
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b) Minimum inhibitory concentration (MIC) test
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c) Time-kill assay
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d) Polymerase chain reaction (PCR)
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What is the Minimum Inhibitory Concentration (MIC)?
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a) The highest concentration of a drug that kills bacteria
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b) The lowest concentration of a drug that inhibits bacterial growth
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c) The highest concentration of a drug that inhibits bacterial growth
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d) The lowest concentration of a drug that kills bacteria
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What is the Minimum Bactericidal Concentration (MBC)?
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a) The highest concentration of a drug that kills bacteria
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b) The lowest concentration of a drug that inhibits bacterial growth
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c) The highest concentration of a drug that inhibits bacterial growth
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d) The lowest concentration of a drug that kills bacteria
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Which of the following methods can determine whether an agent is bactericidal or bacteriostatic?
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a) Kirby-Bauer disk diffusion test
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b) Minimum inhibitory concentration (MIC) test
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c) Time-kill assay
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d) Broth dilution test
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What does a bactericidal agent do to bacterial cells?
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a) Inhibits their growth
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b) Kills them
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c) Allows them to replicate
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d) Neutralizes their toxins
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What is a common characteristic of bacteriostatic agents?
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a) They kill bacteria instantly
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b) They inhibit bacterial growth
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c) They promote bacterial growth
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d) They neutralize bacterial toxins
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In a time-kill assay, what is being measured?
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a) The growth rate of bacteria
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b) The time it takes for bacteria to die
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c) The concentration of bacteria over time
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d) The effectiveness of bacteriostatic agents
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What result indicates a bactericidal effect in a time-kill assay?
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a) No change in bacterial count
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b) Reduction in bacterial count
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c) Increase in bacterial count
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d) Stabilization of bacterial count
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Which agent is more likely to be used for sterilization purposes?
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a) Bactericidal agent
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b) Bacteriostatic agent
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c) Both equally
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d) Neither
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Which agent is more likely to be used in a clinical setting to treat infections?
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a) Bactericidal agent
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b) Bacteriostatic agent
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c) Both equally
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d) Neither
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What does the term \’bactericidal\’ specifically imply about the agent\’s activity?
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a) It stops bacteria from dividing
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b) It kills bacteria
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c) It promotes bacterial growth
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d) It prevents bacterial adherence
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What does the term \’bacteriostatic\’ specifically imply about the agent\’s activity?
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a) It kills bacteria
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b) It inhibits bacterial growth
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c) It promotes bacterial growth
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d) It prevents bacterial adherence
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Which test involves measuring the optical density of a bacterial culture to evaluate the effect of an antimicrobial agent?
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a) Kirby-Bauer disk diffusion test
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b) Broth dilution test
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c) Time-kill assay
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d) Spectrophotometry
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Why is the MIC test important in evaluating antimicrobial agents?
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a) It determines the lowest concentration needed to kill bacteria
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b) It determines the lowest concentration needed to inhibit bacterial growth
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c) It determines the time it takes for bacteria to die
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d) It measures the optical density of a bacterial culture
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What does a clear zone around an antibiotic disk in the Kirby-Bauer test indicate?
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a) Bacterial growth
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b) Bacterial inhibition
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c) Bacterial resistance
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d) Bacterial adherence
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Which agent would be preferred in treating a life-threatening infection where the immune system is compromised?
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a) Bactericidal agent
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b) Bacteriostatic agent
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c) Both equally
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d) Neither
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How can the effectiveness of a bactericidal agent be confirmed after treatment?
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a) By measuring the growth rate of bacteria
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b) By counting the number of surviving bacteria
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c) By observing bacterial adherence
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d) By assessing bacterial metabolic activity
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Which test can be used to differentiate between bactericidal and bacteriostatic effects?
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a) Kirby-Bauer disk diffusion test
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b) Time-kill assay
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c) MIC test
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d) Spectrophotometry
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What is the significance of the MBC in evaluating an antimicrobial agent?
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a) It helps determine the lowest concentration needed to inhibit bacterial growth
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b) It helps determine the lowest concentration needed to kill bacteria
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c) It measures the time required to kill bacteria
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d) It assesses bacterial metabolic activity
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Which type of agent is more likely to be used in a situation where the patient has a strong immune response?
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a) Bactericidal agent
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b) Bacteriostatic agent
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c) Both equally
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d) Neither
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What does a reduction in colony-ing units (CFUs) indicate in a time-kill assay?
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a) Bacterial growth
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b) Bacterial adherence
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c) Bactericidal activity
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d) Bacterial resistance
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Which agent relies on the host\’s immune system to eliminate the bacteria after inhibition of growth?
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a) Bactericidal agent
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b) Bacteriostatic agent
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c) Both equally
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d) Neither
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What is the significance of a time-kill curve in evaluating antimicrobial agents?
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a) It shows the time required to kill bacteria
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b) It shows the concentration required to inhibit bacterial growth
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c) It shows the rate of bacterial resistance
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d) It shows the bacterial adherence rate
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Which agent is more suitable for use in disinfectants and sterilization processes?
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a) Bactericidal agent
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b) Bacteriostatic agent
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c) Both equally
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d) Neither
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How does the presence of biofilm affect the efficacy of bactericidal agents?
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a) It enhances the efficacy
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b) It has no effect
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c) It reduces the efficacy
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d) It neutralizes the agent
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What is a potential disadvantage of using bacteriostatic agents?
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a) They kill bacteria instantly
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b) They require the host\’s immune system to clear the infection
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c) They promote bacterial growth
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d) They neutralize bacterial toxins
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Which agent is more likely to cause the release of endotoxins upon bacterial cell lysis?
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a) Bactericidal agent
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b) Bacteriostatic agent
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c) Both equally
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d) Neither
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Which test would you use to measure the effectiveness of an antimicrobial agent over a 24-hour period?
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a) Kirby-Bauer disk diffusion test
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b) Time-kill assay
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c) MIC test
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d) Broth dilution test
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