Pharmacy Practice MCQ, in this article we will solve, Practice MCQ under subject Microbiology. Read following article for your reference.
Factors Influencing Disinfection, Antiseptics And Their Evaluation » PHARMACAREERS
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Which of the following is a primary factor affecting the efficacy of a disinfectant?
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a) Temperature
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b) Humidity
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c) Light intensity
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d) Air pressure
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What is the term for the time required for a disinfectant to achieve its desired effect?
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a) Exposure time
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b) Reaction time
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c) Contact time
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d) Incubation time
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Which factor can reduce the effectiveness of an antiseptic?
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a) Presence of organic matter
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b) High pH
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c) Low humidity
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d) Room temperature
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What is the main purpose of using antiseptics in healthcare?
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a) To sterilize surgical instruments
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b) To reduce the risk of infection in living tissues
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c) To disinfect hospital floors
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d) To clean laboratory glassware
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Which of the following is a commonly used antiseptic for skin disinfection?
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a) Chlorine
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b) Ethanol
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c) Hydrogen peroxide
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d) Iodine
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What is the term for the lowest concentration of a disinfectant that kills all microorganisms in a test system?
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a) Minimum inhibitory concentration (MIC)
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b) Minimum bactericidal concentration (MBC)
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c) Lethal dose (LD50)
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d) Effective dose (ED50)
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Which method is commonly used to evaluate the efficacy of disinfectants?
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a) Kirby-Bauer disk diffusion test
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b) Serial dilution
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c) Use-dilution test
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d) Polymerase chain reaction (PCR)
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Which factor does NOT influence the activity of disinfectants?
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a) Concentration of the disinfectant
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b) Time of exposure
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c) Size of the microorganisms
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d) Presence of organic matter
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What is the primary mechanism of action for alcohol-based disinfectants?
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a) Denaturing proteins
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b) Oxidizing cell components
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c) Disrupting cell walls
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d) Inhibiting DNA synthesis
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Which of the following can affect the efficacy of antiseptics on the skin?
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a) Skin pH
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b) Skin temperature
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c) Presence of oils
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d) All of the above
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Which type of microorganisms are generally most resistant to disinfectants?
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a) Gram-positive bacteria
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b) Gram-negative bacteria
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c) Fungi
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d) Bacterial spores
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What is the term for the effectiveness of a disinfectant against a specific organism?
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a) Spectrum of activity
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b) Range of effect
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c) Efficacy profile
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d) Antimicrobial index
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Which of the following is an important factor to consider when selecting a disinfectant for use in a healthcare setting?
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a) Toxicity to humans
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b) Cost
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c) Ease of use
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d) All of the above
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What is the mode of action of iodine-based antiseptics?
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a) Disrupting cell membranes
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b) Inhibiting protein synthesis
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c) Oxidizing cellular components
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d) Inhibiting DNA replication
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What is the term for a substance that reduces the number of microorganisms to safe levels?
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a) Disinfectant
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b) Antiseptic
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c) Sanitizer
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d) Sterilant
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Which factor can enhance the effectiveness of disinfectants?
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a) Higher temperature
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b) Lower concentration
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c) Shorter contact time
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d) Presence of organic matter
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Which disinfectant is commonly used in water treatment to kill bacteria and viruses?
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a) Ethanol
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b) Chlorine
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c) Phenol
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d) Quaternary ammonium compounds
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What is the primary function of antiseptics?
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a) To kill microorganisms on non-living surfaces
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b) To kill microorganisms on living tissues
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c) To sterilize surgical instruments
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d) To sanitize food products
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Which of the following can be used as both a disinfectant and an antiseptic?
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a) Hydrogen peroxide
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b) Chlorine
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c) Formaldehyde
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d) Benzalkonium chloride
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Which test is used to determine the resistance of bacteria to antiseptics?
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a) Disk diffusion test
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b) Broth dilution test
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c) Use-dilution test
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d) Minimum inhibitory concentration (MIC) test
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What is the impact of organic matter on the efficacy of disinfectants?
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a) It enhances the efficacy
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b) It has no effect
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c) It reduces the efficacy
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d) It neutralizes the disinfectant
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Which type of antiseptic is commonly used for oral hygiene?
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a) Chlorhexidine
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b) Ethanol
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c) Hydrogen peroxide
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d) Iodine
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What is the mechanism of action of quaternary ammonium compounds?
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a) Oxidizing cell components
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b) Disrupting cell membranes
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c) Inhibiting protein synthesis
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d) Denaturing nucleic acids
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Which of the following factors can influence the contact time required for a disinfectant to be effective?
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a) Concentration of the disinfectant
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b) Type of microorganism
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c) Presence of biofilm
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d) All of the above
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Which disinfectant is known for its broad-spectrum activity and is used in both healthcare and household settings?
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a) Chlorine
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b) Ethanol
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c) Phenol
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d) Quaternary ammonium compounds
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What is the effect of temperature on the activity of disinfectants?
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a) Higher temperature generally increases activity
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b) Lower temperature generally increases activity
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c) Temperature has no effect
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d) Temperature always decreases activity
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Which of the following is an example of a high-level disinfectant?
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a) Isopropanol
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b) Hydrogen peroxide
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c) Sodium hypochlorite
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d) Glutaraldehyde
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What is the term for the ability of a disinfectant to kill bacteria, fungi, and viruses?
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a) Bactericidal
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b) Broad-spectrum
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c) Fungicidal
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d) Virucidal
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What is the primary consideration when evaluating the effectiveness of an antiseptic for surgical hand scrubbing?
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a) Cost
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b) Speed of action
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c) Residual activity
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d) Odor
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Which of the following is a common method used to evaluate the stability of a disinfectant?
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a) Accelerated aging test
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b) Use-dilution test
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c) Disk diffusion test
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d) Broth dilution test
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